Arsenal captain Cesc Fabregas produced an impressive display on his return from injury as the Gunners won 2-0 at Bolton.
The Spain midfielder, who missed three matches with a hamstring injury, scored his 10th league goal of the season in the 28th minute after a neat one-two with Eduardo.
His surging run then led to substitute Fran Merida scoring the second 12 minutes from time as former Wanderers' player Coyle's reign got off to a losing start
Aston Villa 0-0 West Ham
Aston Villa failed to cash in on slip-ups by the group challenging for the 4th Champions League spot drawing 0-0 with West Ham.
Manchester City - beaten at Everton - and Tottenham, held at home by Hull, both dropped points on Saturday.
But a combination of a below-par performance and some fine saves by Robert Green meant Aston Villa had to settle for their first goalless draw of the campaign in the top flight.
Blackburn Rovers 2-0 Fulham
Blackburn grabbed their first Premier League win since November as they beat Fulham 2-0 at Ewood Park.
Chris Samba's was in the right place to deflect home an attempted clearance by former Rover Damien Duff after Benni McCarthy's corner caused havoc in the visitors' box in the 24th minute.
Captain Ryan Nelsen headed a 54th-minute second while Fulham had few moments to savour - the best coming from Clint Dempsey with an overhead kick which struck the bar.
Top 10 Standings in the English Premier League
Pl GD Pts 1 Chelsea 21 +34 48 2 Man Utd 22 +30 47 3 Arsenal 21 +32 45 4 Tottenham 21 +20 38 5 Man City 21 +12 38 6 Aston Villa 21 +11 36 7 Liverpool 21 +12 34 8 Birmingham 21 +2 33 9 Fulham 21 +2 27 10 Everton 21 -4 26