Manchester United are the 11/8 (2.38) favourites for the FA Cup even after being drawn against Portsmouth at Old Trafford in the only all-Premier League last eight tie.
Chelsea are at 2.75 to win the Cup after Avram Grant's men were paired with Liverpool's conquerors Barnsley in the quarter-finals.
Portsmouth were general 6/1 third favourites before the numbers came out but after being drawn away to one of the two big guns they've been pushed out to a general 14/1. (15.00) along with Middlesbrough as the biggest threats to Chelsea and Manchester United.
Boro have home tie against Cardiff. However, they'll still need to beat Sheffield United in a replay at the Riverside before they can pencil in a quarter-final with the Bluebirds.
West Brom were also cut after being drawn away to Bristol Rovers - the only League One side left in the tournament. The Baggies are as short as 12/1 with Sky Bet although Boylesports have them at 20s.
Cardiff are 51.00 with BetFred, while Canbet offer 151.00 on Barnsley, and Centrebet are 151.00 for Bristol Rovers.
Paddy Power are offering 3/1 (4.00) for any club except Manchester United and Chelsea lifting the trophy and 7/4 (2.75) for a non-Premier League team to reach the final.
Top Odds :
Manchester United @ 2.38 at Bet365
Chelsea @ 2.75 at Centrebet
Middlesbrough @ 15.00 at Centrebet
Portsmouth @ 15.00 at Betfred
